All four major interstates heading to downtown St. Louis have at least one closure following flash flooding early Tuesday morning.

At 3:30 a.m., first responders blocked off all lanes of eastbound Interstate 64 near Grand.

It reopened just before 7 a.m. Tuesday.

It reopened just before 7 a.m. Tuesday.

On Interstate 55, drivers were diverted off the highway before Potomac.

Eastbound Interstate 44 is the third interstate affected. All lanes were closed at Hampton.

Just past 6 a.m., the St. Louis Fire Department reported several cars stranded on Interstate 44 near Jefferson Avenue.

Drivers would have to find an alternate route on eastbound Interstate 70 near Natural Bridge and Jennings Station Road.

In addition, Interstate 70 was closed in both directions near Mid Rivers Mall in St. Charles.